A-349821

A-349821

Identifiers
IUPAC name [4-[4-[3-[(2R,5R)-2,5-dimethylpyrrolidin-1-yl]propoxy]phenyl]phenyl]-morpholin-4-ylmethanone
CAS Number	372513-99-0 N 556835-30-4 (trifluoroacetate salt)
PubChem CID	9954017
IUPHAR/BPS	1217
ChemSpider	8129627 Y
UNII	67WL275ISI
ChEMBL	ChEMBL179702 Y
CompTox Dashboard (EPA)	DTXSID701116601
Chemical and physical data
Formula	C26H34N2O3
Molar mass	422.569 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@@H]1CC[C@H](N1CCCOC2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N4CCOCC4)C
InChI InChI=1S/C26H34N2O3/c1-20-4-5-21(2)28(20)14-3-17-31-25-12-10-23(11-13-25)22-6-8-24(9-7-22)26(29)27-15-18-30-19-16-27/h6-13,20-21H,3-5,14-19H2,1-2H3/t20-,21-/m1/s1 Y Key:CFUHKRLMDNFZED-NHCUHLMSSA-N Y
NY (what is this?)  (verify)

A-349,821 is a potent and selective histamine H₃ receptor antagonist^[1] (or possibly an inverse agonist).^[2] It has nootropic effects in animal studies,^[3] although there do not appear to be any plans for clinical development at present and it is currently only used in laboratory research.^{[citation needed]}

See also

• H₃ receptor antagonist

References

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