Ditazole

Chemical compound

B01AC01 (WHO)

Identifiers

IUPAC name

2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanol

CAS Number

18471-20-0^Y

PubChem CID

29088

DrugBank

DB08994^N

ChemSpider

27061^N

UNII

H2BQI5Z8FT

KEGG

D07138^Y

CompTox Dashboard (EPA)

DTXSID3022954

ECHA InfoCard100.038.488

Chemical and physical dataFormulaC₁₉H₂₀N₂O₃Molar mass324.380 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

C1=CC=C(C=C1)C2=C(OC(=N2)N(CCO)CCO)C3=CC=CC=C3

InChI

InChI=1S/C19H20N2O3/c22-13-11-21(12-14-23)19-20-17(15-7-3-1-4-8-15)18(24-19)16-9-5-2-6-10-16/h1-10,22-23H,11-14H2^N
Key:UUCMDZWCRNZCOY-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

Ditazole is a non-steroidal anti-inflammatory agent with analgesic and antipyretic activity similar to phenylbutazone.^[1] It is also a platelet aggregation inhibitor which is marketed in Spain and Portugal under the trade name Ageroplas.^[2]

References

^ "Ditazole". PubChem. U.S. National Library of Medicine.
^ Budavari S, O'Neil M, Smith A, Heckelman P, Obenchain J (1996). The Merck index : an encyclopedia of chemicals, drugs, and biologicals (12th ed.). Whitehouse Station, NJ: Merck. ISBN 978-0-911910-12-4. 3432.

Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)

Antiplatelet drugs

Glycoprotein IIb/IIIa inhibitors	Abciximab Eptifibatide Orbofiban Roxifiban Sibrafiban^§ Tirofiban
ADP receptor/P2Y₁₂ inhibitors	Thienopyridines Clopidogrel Prasugrel Ticlopidine Nucleotide/nucleoside analogs Cangrelor Elinogrel Ticagrelor
Prostaglandin analogue (PGI2)	Beraprost Iloprost Prostacyclin Treprostinil
COX inhibitors	Acetylsalicylic acid/Aspirin^# Aloxiprin Carbasalate calcium Indobufen Triflusal
Thromboxane inhibitors	Thromboxane synthase inhibitors Dipyridamole (+ aspirin) Picotamide Terbogrel Receptor antagonists Terbogrel Terutroban^§
Phosphodiesterase inhibitors	Cilostazol Dipyridamole Triflusal
Other	Cloricromen Ditazole Vorapaxar

Anticoagulants

Vitamin K antagonists
(inhibit II, VII, IX, X)

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	Low-molecular-weight heparin Bemiparin Certoparin Dalteparin Enoxaparin Nadroparin Parnaparin Reviparin Tinzaparin Oligosaccharides Fondaparinux Idraparinux^§ Heparinoids Danaparoid Dermatan sulfate Sulodexide
Direct Xa inhibitors ("xabans")	Apixaban Betrixaban Darexaban^§ Edoxaban Otamixaban^§ Rivaroxaban