Lymphoepithelioma

Medical condition
Lymphoepithelioma
Other namesSchmincke–Regaud tumor
Nasopharyngeal lymphoepithelioma in a lymph node. Note the small, blue lymphocytes between the larger cancer cells.
SpecialtyOncology

Lymphoepithelioma is a type of poorly differentiated nasopharyngeal carcinoma characterized by prominent infiltration of lymphocytes in the area involved by tumor. Lymphoepithelioma is also known as "class III nasopharyngeal carcinoma" in the WHO classification system. It has a high tendency to metastasize and is responsive to radiotherapy. Most cases are associated with Epstein–Barr virus infection.[1]

Lymphoepithelioma-like carcinomas are carcinomas that arise outside of the nasopharynx, but resemble a lymphoepithelioma histologically. Lymphoepithelioma-like carcinomas may be found in almost any epithelial organ, including the lung, thymus, breast, colon, endometrium, prostate, and skin,[1] as well as urinary bladder, trachea, esophagus, stomach, salivary glands, vulva.[2]

History

Lymphoepithelioma may also be referred to as Schmincke–Regaud tumor, after the German pathologist Alexander Schminke and French radiologist Claude Regaud.

References

  1. ^ a b Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor) (2003). Modern Surgical Pathology (2 Volume Set). London: W B Saunders. ISBN 0-7216-7253-1. {{cite book}}: |author= has generic name (help)CS1 maint: multiple names: authors list (link)
  2. ^ Juan Rosai. Rosai and Ackerman's Surgical Pathology. 9th edition

External links

Classification
D
  • v
  • t
  • e
Glandular and epithelial cancer
Epithelium
Papilloma/carcinoma
Complex epithelial
Glands
Adenomas/
adenocarcinomas
Gastrointestinal
Urogenital
Endocrine
Other/multiple
Adnexal and
skin appendage
Cystic,
mucinous,
and serous
Cystic general
Mucinous
Serous
Ductal,
lobular,
and medullary
Ductal carcinoma
Lobular carcinoma
Medullary carcinoma
Acinar cell