MSTO1

Protein-coding gene in the species Homo sapiens

MSTO1

Identifiers

Aliases

MSTO1, MST, LST005, misato 1, mitochondrial distribution and morphology regulator, MMYAT, misato mitochondrial distribution and morphology regulator 1

External IDs

OMIM: 617619; MGI: 2385175; HomoloGene: 41228; GeneCards: MSTO1; OMA:MSTO1 - orthologs

Gene location (Human)

Chr.	Chromosome 1 (human)^[1]

Band	1q22	Start	155,610,205 bp^[1]
Band	1q22	End	155,614,951 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)^[2]

Band	3\|3 F1	Start	88,812,414 bp^[2]
Band	3\|3 F1	End	88,821,306 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

left testis

right testis

pituitary gland

right ovary

anterior pituitary

left ovary

tibial nerve

right uterine tube

body of uterus

right lobe of thyroid gland

Top expressed in

spermatid

yolk sac

spermatocyte

seminiferous tubule

epiblast

internal carotid artery

embryo

external carotid artery

embryo

primitive streak

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	molecular function
Cellular component	mitochondrial outer membrane mitochondrion membrane cytoplasm
Biological process	mitochondrion organization mitochondrion distribution mitochondrial genome maintenance mitotic sister chromatid segregation mitotic spindle assembly
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


55154


229524

Ensembl


ENSG00000125459


ENSMUSG00000068922

UniProt


Q9BUK6


Q2YDW2

RefSeq (mRNA)

NM_001256532 NM_001256533 NM_018116 NM_001350772 NM_001350773
NM_001350774 NM_001350775 NM_001350776 NM_001350777 NM_001350778 NM_001350779 NM_001350780 NM_001350781 NM_001350782 NM_001350783 NM_001350784 NM_001350785 NM_001350786 NM_001350787 NM_001350788 NM_001350789


NM_144898

RefSeq (protein)

NP_001243461 NP_001243462 NP_060586 NP_001337701 NP_001337702
NP_001337703 NP_001337704 NP_001337705 NP_001337706 NP_001337707 NP_001337708 NP_001337709 NP_001337710 NP_001337711 NP_001337712 NP_001337713 NP_001337714 NP_001337715 NP_001337716 NP_001337717 NP_001337718


NP_659147

Location (UCSC)

Chr 1: 155.61 – 155.61 Mb

Chr 3: 88.81 – 88.82 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Protein misato homolog 1 is a protein that in humans is encoded by the MSTO1 gene.^[5]^[6]

The MSTO1 gene is 5134 base pairs (located in chromosome 1) and the MSTO1 protein is 570 aminoacids in length. It is located in the outer membrane of the mitochondrion, and is involved in the regulation of mitochondrial distribution and morphology.^[7]

Structure

The misato protein contains an N-terminal misato segment II myosin-like domain and a central tubulin domain.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125459 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068922 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kuryshev VY, Vorobyov E, Zink D, Schmitz J, Rozhdestvensky TS, Munstermann E, Ernst U, Wellenreuther R, Moosmayer P, Bechtel S, Schupp I, Horst J, Korn B, Poustka A, Wiemann S (Jul 2006). "An anthropoid-specific segmental duplication on human chromosome 1q22". Genomics. 88 (2): 143–51. doi:10.1016/j.ygeno.2006.02.002. PMID 16545939.
^ "Entrez Gene: MSTO1 misato homolog 1 (Drosophila)".
^ ^a ^b Kimura M, Okano Y (April 2007). "Human Misato regulates mitochondrial distribution and morphology". Exp. Cell Res. 313 (7): 1393–404. doi:10.1016/j.yexcr.2007.02.004. PMID 17349998.