PIP5K1A |
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Identifiers |
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Aliases | PIP5K1A, phosphatidylinositol-4-phosphate 5-kinase type 1 alpha |
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External IDs | OMIM: 603275; MGI: 107929; HomoloGene: 93492; GeneCards: PIP5K1A; OMA:PIP5K1A - orthologs |
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Gene location (Human) |
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![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
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| Band | 1q21.3 | Start | 151,197,949 bp[1] |
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End | 151,249,536 bp[1] |
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Gene location (Mouse) |
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![Chromosome 3 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Ideogram_house_mouse_chromosome_3.svg/260px-Ideogram_house_mouse_chromosome_3.svg.png) | Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 F2.1 | Start | 95,058,530 bp[2] |
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End | 95,106,930 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right testis
- epithelium of colon
- left testis
- sural nerve
- Achilles tendon
- gastric mucosa
- skin of leg
- left uterine tube
- skin of abdomen
- islet of Langerhans
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| Top expressed in | - gastrula
- Rostral migratory stream
- decidua
- olfactory tubercle
- cumulus cell
- CA3 field
- dentate gyrus
- pineal gland
- dentate gyrus of hippocampal formation granule cell
- primary motor cortex
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PBB_GE_PIP5K1A_207391_s_at_fs.png/250px-PBB_GE_PIP5K1A_207391_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/4/4b/PBB_GE_PIP5K1A_210256_s_at_fs.png/250px-PBB_GE_PIP5K1A_210256_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- 1-phosphatidylinositol-4-phosphate 5-kinase activity
- kinase activity
- kinase binding
- protein binding
- phosphatidylinositol phosphate kinase activity
- ATP binding
- 1-phosphatidylinositol-3-phosphate 5-kinase activity
- 1-phosphatidylinositol-5-kinase activity
- phosphatidylinositol-3,4-bisphosphate 5-kinase activity
- 1-phosphatidylinositol-3-phosphate 4-kinase activity
| Cellular component | - nuclear speck
- mRNA cleavage and polyadenylation specificity factor complex
- cell projection
- membrane
- focal adhesion
- ruffle
- plasma membrane
- nucleoplasm
- ruffle membrane
- nucleus
- lamellipodium
- cytoplasm
- cytosol
| Biological process | - fibroblast migration
- actin cytoskeleton reorganization
- phosphatidylinositol metabolic process
- activation of GTPase activity
- phosphorylation
- keratinocyte differentiation
- focal adhesion assembly
- phospholipid biosynthetic process
- phagocytosis
- cell chemotaxis
- glycerophospholipid metabolic process
- ruffle assembly
- cell migration
- signal transduction
- phosphatidylinositol phosphate biosynthetic process
- regulation of phosphatidylinositol 3-kinase signaling
- phosphatidylinositol biosynthetic process
- protein localization to plasma membrane
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001135636 NM_001135637 NM_001135638 NM_003557 NM_001330689 |
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RefSeq (protein) | |
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NP_001129108 NP_001129109 NP_001129110 NP_001317618 NP_003548 |
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Location (UCSC) | Chr 1: 151.2 – 151.25 Mb | Chr 3: 95.06 – 95.11 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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