Protein-coding gene in the species Homo sapiens
SHCBP1L |
---|
|
Identifiers |
---|
Aliases | SHCBP1L, C1orf14, GE36, SHC binding and spindle associated 1 like |
---|
External IDs | MGI: 1919086; HomoloGene: 12800; GeneCards: SHCBP1L; OMA:SHCBP1L - orthologs |
---|
Gene location (Human) |
---|
![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
---|
| Band | 1q25.3 | Start | 182,899,865 bp[1] |
---|
End | 182,953,525 bp[1] |
---|
|
Gene location (Mouse) |
---|
![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
---|
| Band | 1|1 G3 | Start | 153,300,908 bp[2] |
---|
End | 153,328,320 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - sperm
- right testis
- left testis
- testicle
- gastric mucosa
- apex of heart
- embryo
- ventricular zone
- ganglionic eminence
- human musculoskeletal system
|
| Top expressed in | - spermatocyte
- spermatid
- seminiferous tubule
- otolith organ
- utricle
- secondary oocyte
- primary oocyte
- zygote
- Gonadal ridge
- substantia nigra
|
| More reference expression data |
|
---|
BioGPS | |
---|
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protein) | | |
---|
Location (UCSC) | Chr 1: 182.9 – 182.95 Mb | Chr 1: 153.3 – 153.33 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|
SHC binding and spindle associated 1 like is a protein that in humans is encoded by the SHCBP1L gene. [5]
Function
This gene encodes a Src homology 2 domain-binding protein 1-like protein. The encoded protein interacts with heat shock 70 kDa protein 2 and may be involved in maintaining spindle integrity during meiosis. This gene is located in region of chromoso0me 1 encompassing a prostate cancer susceptibility locus. [provided by RefSeq, Sep 2016].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000157060 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042708 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: SHC binding and spindle associated 1 like". Retrieved 2018-06-26.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.