Shc binding and spindle associated 1 like

Protein-coding gene in the species Homo sapiens
SHCBP1L
Identifiers
AliasesSHCBP1L, C1orf14, GE36, SHC binding and spindle associated 1 like
External IDsMGI: 1919086; HomoloGene: 12800; GeneCards: SHCBP1L; OMA:SHCBP1L - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for SHCBP1L
Genomic location for SHCBP1L
Band1q25.3Start182,899,865 bp[1]
End182,953,525 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for SHCBP1L
Genomic location for SHCBP1L
Band1|1 G3Start153,300,908 bp[2]
End153,328,320 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sperm

  • right testis

  • left testis

  • testicle

  • gastric mucosa

  • apex of heart

  • embryo

  • ventricular zone

  • ganglionic eminence

  • human musculoskeletal system
Top expressed in
  • spermatocyte

  • spermatid

  • seminiferous tubule

  • otolith organ

  • utricle

  • secondary oocyte

  • primary oocyte

  • zygote

  • Gonadal ridge

  • substantia nigra
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

81626

71836

Ensembl

ENSG00000157060

ENSMUSG00000042708

UniProt

Q9BZQ2

Q3TTP0

RefSeq (mRNA)

NM_030933
NM_001345928

NM_001033162

RefSeq (protein)

NP_001332857
NP_112195

NP_001028334

Location (UCSC)Chr 1: 182.9 – 182.95 MbChr 1: 153.3 – 153.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SHC binding and spindle associated 1 like is a protein that in humans is encoded by the SHCBP1L gene. [5]

Function

This gene encodes a Src homology 2 domain-binding protein 1-like protein. The encoded protein interacts with heat shock 70 kDa protein 2 and may be involved in maintaining spindle integrity during meiosis. This gene is located in region of chromoso0me 1 encompassing a prostate cancer susceptibility locus. [provided by RefSeq, Sep 2016].

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000157060 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042708 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: SHC binding and spindle associated 1 like". Retrieved 2018-06-26.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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