TMEM9

Protein-coding gene in the species Homo sapiens
TMEM9
Identifiers
AliasesTMEM9, TMEM9A, DERM4, transmembrane protein 9
External IDsOMIM: 616877; MGI: 1913491; HomoloGene: 9515; GeneCards: TMEM9; OMA:TMEM9 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for TMEM9
Genomic location for TMEM9
Band1q32.1Start201,134,772 bp[1]
End201,171,574 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for TMEM9
Genomic location for TMEM9
Band1|1 E4Start135,935,888 bp[2]
End135,963,080 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • cingulate gyrus

  • anterior cingulate cortex

  • hypothalamus

  • right adrenal gland

  • right adrenal cortex

  • right frontal lobe

  • left adrenal gland

  • left adrenal cortex

  • nucleus accumbens

  • Brodmann area 9
Top expressed in
  • neural layer of retina

  • yolk sac

  • dentate gyrus of hippocampal formation granule cell

  • saccule

  • right kidney

  • ventricular zone

  • primary visual cortex

  • otic vesicle

  • lens

  • superior frontal gyrus
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • molecular function
Cellular component
  • integral component of membrane
  • lysosomal membrane
  • endosome
  • late endosome
  • lysosome
  • membrane
  • late endosome membrane
Biological process
  • biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

252839

66241

Ensembl

ENSG00000116857

ENSMUSG00000026411

UniProt

Q9P0T7

Q9CR23

RefSeq (mRNA)
NM_001288564
NM_001288565
NM_001288566
NM_001288567
NM_001288568

NM_001288569
NM_001288570
NM_001288571
NM_016456

NM_001160145
NM_001160146
NM_025439

RefSeq (protein)
NP_001275493
NP_001275494
NP_001275495
NP_001275496
NP_001275497

NP_001275498
NP_001275499
NP_001275500
NP_057540

NP_001153617
NP_001153618
NP_079715

Location (UCSC)Chr 1: 201.13 – 201.17 MbChr 1: 135.94 – 135.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane protein 9 is a protein that in humans is encoded by the TMEM9 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116857 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026411 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: TMEM9 transmembrane protein 9".

Further reading

  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Kveine M, Tenstad E, Døsen G, et al. (2002). "Characterization of the novel human transmembrane protein 9 (TMEM9) that localizes to lysosomes and late endosomes". Biochem. Biophys. Res. Commun. 297 (4): 912–7. doi:10.1016/S0006-291X(02)02228-3. hdl:10852/27931. PMID 12359240.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.


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