TTC28

Protein-coding gene in the species Homo sapiens
TTC28
Identifiers
AliasesTTC28, TPRBK, tetratricopeptide repeat domain 28
External IDsOMIM: 615098; MGI: 2140873; HomoloGene: 41023; GeneCards: TTC28; OMA:TTC28 - orthologs
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for TTC28
Genomic location for TTC28
Band22q12.1Start27,978,014 bp[1]
End28,679,840 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for TTC28
Genomic location for TTC28
Band5|5 FStart111,027,669 bp[2]
End111,437,646 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • ganglionic eminence

  • corpus epididymis

  • synovial joint

  • tibia

  • secondary oocyte

  • urethra

  • germinal epithelium

  • parietal pleura

  • visceral pleura

  • parotid gland
Top expressed in
  • Rostral migratory stream

  • saccule

  • epithelium of lens

  • human fetus

  • ganglionic eminence

  • otic vesicle

  • internal carotid artery

  • external carotid artery

  • otic placode

  • lacrimal gland
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • kinase binding
Cellular component
  • cytoplasm
  • microtubule organizing center
  • spindle
  • spindle pole
  • cytoskeleton
  • midbody
  • mitotic spindle
Biological process
  • cell cycle
  • cell division
  • regulation of mitotic cell cycle
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

23331

209683

Ensembl

ENSG00000100154

ENSMUSG00000033209

UniProt

Q96AY4

Q80XJ3

RefSeq (mRNA)

NM_001145418
NM_015281
NM_001393403
NM_001393404
NM_001393405

NM_001267622
NM_024477

RefSeq (protein)

NP_001138890

NP_001254551

Location (UCSC)Chr 22: 27.98 – 28.68 MbChr 5: 111.03 – 111.44 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tetratricopeptide repeat domain 28 is a protein that in humans is encoded by the TTC28 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100154 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033209 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Tetratricopeptide repeat domain 28".

Further reading

  • Izumiyama T, Minoshima S, Yoshida T, Shimizu N (December 2012). "A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis". Gene. 511 (2): 202–17. doi:10.1016/j.gene.2012.09.061. PMID 23036704.
  • Wang K, Li WD, Zhang CK, Wang Z, Glessner JT, Grant SF, Zhao H, Hakonarson H, Price RA (April 2011). "A genome-wide association study on obesity and obesity-related traits". PLOS One. 6 (4): e18939. Bibcode:2011PLoSO...618939W. doi:10.1371/journal.pone.0018939. PMC 3084240. PMID 21552555.


  • v
  • t
  • e