CD200 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/4/4d/CD200.png/250px-CD200.png) |
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Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants |
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Aliases | CD200 |
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IDs externes | OMIM: 155970 MGI: 1196990 HomoloGene: 4344 GeneCards: CD200 |
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Position du gène (Homme) |
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![Chromosome 3 humain](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 humain[1] |
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| Locus | 3q13.2 | Début | 112,332,347 bp[1] |
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Fin | 112,362,812 bp[1] |
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Position du gène (Souris) |
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![Chromosome 16 (souris)](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/Ideogram_house_mouse_chromosome_16.svg/260px-Ideogram_house_mouse_chromosome_16.svg.png) | Chr. | Chromosome 16 (souris)[2] |
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| Locus | 16 B5|16 29.53 cM | Début | 45,202,498 bp[2] |
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Fin | 45,229,416 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - frontal pole
- éminence ganglionnaire
- Brodmann area 10
- gyrus frontal moyen
- hypothalamus
- cortex orbitofrontal
- Brodmann area 9
- parietal pleura
- Brodmann area 46
- Brodmann area 23
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| Fortement exprimé dans | - aorte ascendante
- tunica media of zone of aorta
- Aire tegmentale ventrale
- dorsomedial hypothalamic nucleus
- ventromedial nucleus
- noyau paraventriculaire de l'hypothalamus
- Noyau suprachiasmatique
- corps du fémur
- noyau arqué
- valve aortique
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| Plus de données d'expression de référence |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/1/15/PBB_GE_CD200_209583_s_at_fs.png/250px-PBB_GE_CD200_209583_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PBB_GE_CD200_209582_s_at_fs.png/250px-PBB_GE_CD200_209582_s_at_fs.png) | Plus de données d'expression de référence |
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Gene Ontology |
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Fonction moléculaire | - signaling receptor binding
- liaison protéique
- protein homodimerization activity
- cell adhesion molecule binding
- protein binding involved in heterotypic cell-cell adhesion
- glycosylated region protein binding
| Composant cellulaire | - integral component of membrane
- integral component of plasma membrane
- membrane
- membrane plasmique
- surface cellulaire
- axone
- neuron projection
- neuronal cell body
- cell body
| Processus biologique | - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
- cell recognition
- homophilic cell adhesion via plasma membrane adhesion molecules
- negative regulation of macrophage activation
- regulation of immune response
- negative regulation of leukocyte activation
- negative regulation of cell population proliferation
- negative regulation of NF-kappaB transcription factor activity
- positive regulation of CREB transcription factor activity
- heterotypic cell-cell adhesion
- positive regulation of transforming growth factor beta production
- cell-cell adhesion
- positive regulation of arginase activity
- positive regulation of protein-glutamine gamma-glutamyltransferase activity
- regulation of neuroinflammatory response
- negative regulation of neuroinflammatory response
- negative regulation of neuron death
- negative regulation of matrix metallopeptidase secretion
- negative regulation of macrophage migration
- negative regulation of T cell migration
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001004196 NM_001004197 NM_005944 NM_001318826 NM_001318828
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NM_001318830 NM_001365851 NM_001365852 NM_001365853 NM_001365854 NM_001365855 |
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RefSeq (protéine) | NP_001004196 NP_001305755 NP_001305757 NP_001305759 NP_005935
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NP_001352780 NP_001352781 NP_001352782 NP_001352783 NP_001352784 |
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Localisation (UCSC) | Chr 3: 112.33 – 112.36 Mb | Chr 16: 45.2 – 45.23 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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