Alprenoxime
Chemical compound
- None
- 1-(2-allylphenoxy)-3-(isopropylamino)propan-2-one oxime
- 118552-63-9 Y
- 5489436
- 4590144 Y
- ChEMBL2105963 N
- Interactive image
- O(c1ccccc1C\C=C)C\C(=N\O)CNC(C)C
InChI
- InChI=1S/C15H22N2O2/c1-4-7-13-8-5-6-9-15(13)19-11-14(17-18)10-16-12(2)3/h4-6,8-9,12,16,18H,1,7,10-11H2,2-3H3/b17-14+ Y
- Key:XFQFSSGNEFUEPA-SAPNQHFASA-N Y
Alprenoxime is a beta blocker.[1] It is a prodrug to alprenolol.[1]
References
- ^ a b Prokai L, Wu WM, Somogyi G, Bodor N (May 1995). "Ocular delivery of the beta-adrenergic antagonist alprenolol by sequential bioactivation of its methoxime analogue". Journal of Medicinal Chemistry. 38 (11): 2018–20. doi:10.1021/jm00011a021. PMID 7783133.
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(antagonize α-adrenergic
vasoconstriction)
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Peripheral |
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Serotonin receptor antagonists | |
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Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension) |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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