Domesticine
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| IUPAC name 2-Methoxy-2′H-[1,3]dioxolo[4′,5′:9,10]aporphin-1-ol | |
| Systematic IUPAC name (6aS)-2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H,10H-benzo[de][1,3]benzodioxolo[5,6-g]quinolin-1-ol | |
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Chemical formula | C19H19NO4 |
| Molar mass | 325.364 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references | |
Chemical compound
Domesticine is an α1D-adrenergic receptor antagonist.[1] The compound belongs to the group of Aporphine alkaloids.
References
- ^ Indra, B; Matsunaga, K; Hoshino, O; Suzuki, M; Ogasawara, H; Muramatsu, I; Taniguchi, T; Ohizumi, Y (2002). "(+/-)-Domesticine, a novel and selective alpha1D-adrenoceptor antagonist in animal tissues and human alpha 1-adrenoceptors". European Journal of Pharmacology. 445 (1–2): 21–9. doi:10.1016/s0014-2999(02)01601-1. PMID 12065190.
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Adrenergic receptor modulators
- See also: Receptor/signaling modulators
- Dopaminergics
- Serotonergics
- Monoamine reuptake inhibitors
- Monoamine releasing agents
- Monoamine metabolism modulators
- Monoamine neurotoxins
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